The 24-year-old striker scored his 10th CAF Champions League goal this season away in Lubumbashi to inspire Bekerum from 2-0 at half time to finish level.
Mazembe looked like they were heading to their first Group B win after Tresor Mputu tried to steal the show with his first half brace in the 11th and 32nd minutes to stun the Champions League group stage newcomers.
However, Clottey lived up to his pre-match promise scoring his first from the spot in the 71st minute and earned the point for Bekerum six minutes from time.
Berekum stay top on four points until late Sunday evening ahead of the big Cairo Group A derby between second placed Al Ahly on three points and bottom placed Zamalek.
Zamalek are seeking their first win after losing 3-2 away to Berekum Chelsea in their opening Group A match on July 7 in Accra in a match Clottey scored a hat trick.
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