HIV CURE: Eureka! Toxin in bee venom kills HIV

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at 07:05 PM, 17 Mar 13 (4 years ago)
(8563 | Hero) (m)
An important step toward developing a v*g*nal gel that may prevent the spread of human immuno deficiency virus, HIV, may have been achieved following the discovery that nanoparticles carrying a toxin found in bee venom can destroy HIV while leaving surrounding cells unharmed.



Researchers at Washington University School of Medicine in St. Louis who made discovery which is published the current issue of Antiviral Therapy, hope that in places where HIV is running rampant, people could use this gel as a preventive measure to stop the initial infection.

Bee venom contains a potent toxin called melittin that can poke holes in the protective envelope that surrounds HIV, and other viruses. Large amounts of free melittin can cause a lot of damage. Indeed, in addition to anti-viral therapy..

The new study shows that melittin loaded onto these nanoparticles does not harm normal cells. That’s because Hood added protective bumpers to the nanoparticle surface. When the nanoparticles come into contact with normal cells, which are much larger in size, the particles simply bounce off. HIV, on the other hand, is even smaller than the nanoparticle, so HIV fits between the bumpers and makes contact with the surface of the nanoparticle, where the bee toxin awaits.

Melittin on the nanoparticles fuses with the viral envelope. The melittin forms little pore-like attack complexes and ruptures the envelope, stripping it off the virus.

An advantage of this approach is that the nanoparticle attacks an essential part of the virus’ structure. In contrast, most anti-HIV drugs inhibit the virus’s ability to replicate. But this anti-replication strategy does nothing to stop initial infection, and some strains of the virus have found ways around these drugs and reproduce anyway.

The scientists, who say they are attacking an inherent physical property of HIV, note that, theoretically, there isn’t any way for the virus to adapt to that. The virus has to have a protective coat, a double-layered membrane that covers the virus.

Beyond prevention in the form of a v*g*nal gel, there is potential for using nanoparticles with melittin as therapy for existing HIV infections, especially those that are drug-resistant. The nanoparticles could be injected intravenously and, in theory, would be able to clear HIV from the blood stream.

The basic particle that we are using in these experiments was developed many years ago as an artificial blood product. Although it didn’t work very well for delivering oxygen, but it circulates safely in the body and gives nice platform that can be adapted to fight different kinds of infections.
Since melittin attacks double-layered membranes indiscriminately, this concept is not limited to HIV. Many viruses, including hepatitis B and C, rely on the same kind of protective envelope and would be vulnerable to melittin-loaded nanoparticles.
praytoGod4help at 07:48 PM, 17 Mar 13 (4 years ago)
(272 | Upcoming) (m)
Another story
Reply
emexix at 07:53 PM, 17 Mar 13 (4 years ago)
(37 | Newbie) (m)
Ehen.... Means skin to skin without fear. Yeeeeeehhhh
Reply
beatrice22 at 08:02 PM, 17 Mar 13 (4 years ago)
(106 | Upcoming) (f)
Quote from: emexix on 07:53 PM, 17 Mar 13
Ehen.... Means skin to skin without fear. Yeeeeeehhhh
do u know what u are saying? may God help u.
Reply
zoe61 at 08:19 PM, 17 Mar 13 (4 years ago)
(15337 | Hero) (f)
 Grin Grin Grin Grin
Reply
etibaba at 08:23 PM, 17 Mar 13 (4 years ago)
(4165 | Gistmaniac) (m)
Quote from: emexix on 07:53 PM, 17 Mar 13
Ehen.... Means skin to skin without fear. Yeeeeeehhhh
I pity u

Reply
micc at 08:32 PM, 17 Mar 13 (4 years ago)
(9728 | Hero) (m)
Thank God am married so I don't need it at all at all
Reply
PidginMOUTH at 08:35 PM, 17 Mar 13 (4 years ago)
(8563 | Hero) (m)
oboy Micc u still need am o  Grin Grin Grin Grin
Reply
Starship at 08:37 PM, 17 Mar 13 (4 years ago)
(304 | Upcoming) (m)
Useless discovery.... Prevention is better than cure.... Wetn be science to God's WORD???
Reply
Keffejude at 08:40 PM, 17 Mar 13 (4 years ago)
(2048 | Gistmaniac) (m)
Quote from: beatrice22 on 08:02 PM, 17 Mar 13
do u know what u are saying? may God help u.
Sharrrap there although its obvious d poster is simply playing a prank, na una when dey form dey 4k pass mtchew backyard ashawo...when last did u go 4 an HIV test?  Angry
Reply
1daful at 08:47 PM, 17 Mar 13 (4 years ago)
(2078 | Gistmaniac) (f)
Another lies.

Reply
steve232 at 08:49 PM, 17 Mar 13 (4 years ago)
(1455 | Gistmaniac) (m)
Quote from: emexix on 07:53 PM, 17 Mar 13
Ehen.... Means skin to skin without fear. Yeeeeeehhhh
hmmm Roll Eyes Roll Eyes Roll Eyes Roll Eyes
Reply
paulohking at 09:21 PM, 17 Mar 13 (4 years ago)
(12354 | Hero) (m)
Hope it is a true discovery
Reply
dlimelite at 09:35 PM, 17 Mar 13 (4 years ago)
(14078 | Hero) (f)
hmmmm
Reply
oxSleekxo at 09:48 PM, 17 Mar 13 (4 years ago)
(22 | Newbie) (f)
[color=greenhmmm bees?? Goodluck!!][/color]

Reply
beatrice22 at 10:07 PM, 17 Mar 13 (4 years ago)
(106 | Upcoming) (f)
Quote from: Keffejude on 08:40 PM, 17 Mar 13
Sharrrap there although its obvious d poster is simply playing a prank, na una when dey form dey 4k pass mtchew backyard ashawo...when last did u go 4 an HIV test?  Angry
nobody say make u nor 4k as u like, ok ?  if u like 4k dog ,H:I:V nor dey show 4 face. mtchewwwwwwwwww. u dey go do H:I:V test everyday because u dey 4k anyhow like dog,... go and get a life , AIDS is real
Reply
NYPDmike at 11:35 PM, 17 Mar 13 (4 years ago)
(313 | Upcoming) (m)
Stay out of crime people....................
Reply
osarobo62 at 11:48 PM, 17 Mar 13 (4 years ago)
(10664 | Hero) (m)
Quote from: emexix on 07:53 PM, 17 Mar 13
Ehen.... Means skin to skin without fear. Yeeeeeehhhh
Grin Grin Grin Grin in your dream
Reply
osarobo62 at 11:50 PM, 17 Mar 13 (4 years ago)
(10664 | Hero) (m)
Quote from: micc on 08:32 PM, 17 Mar 13
Thank God am married so I don't need it at all at all
Nice to have a trusted partner and be trusted.
Reply
nzewyte at 12:00 AM, 18 Mar 13 (4 years ago)
(4948 | Gistmaniac) (m)
Ur comments r all laughable...... Permit 2 laff.........

Reply
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