((HIV/AID)) significant breakthrough in HIV/AIDS research

at 09:02 AM, 22/09/2011 (6 years ago)
(64 | Newbie) (m)
Body & Mind - HEALTH
U.S. Gamers Crack Puzzle in AIDS Research that Stumped Scientists for Years

Published September 19, 2011

| NewsCore

      Print
      Email
      Share

Foldit

University of Washington

Foldit is an experimental video game about protein folding that produces real-world results.

In just three weeks, online gamers deciphered the structure of a retrovirus protein that has stumped scientists for over a decade, and a study out Sunday says their breakthrough opens doors for a new AIDS drug design.

The protein, called a protease, plays a critical role in how some viruses, including HIV, multiply. Intensive research has been underway to find AIDS drugs that can deactivate proteases, but scientists were hampered by their inability to crack the enzyme's structure.

Looking for a solution, researchers at the University of Washington turned to Foldit, a program created by the university a few years ago that transforms problems of science into competitive computer games, and challenged players to use their three-dimensional problem-solving skills to build accurate models of the protein.

With days, the gamers generated models good enough for the researchers to refine into an accurate portrayal of the enzyme's structure. What's more, the scientists identified parts of the molecule that are likely targets for drugs to block the enzyme.

"These features provide opportunities for the design of antiretroviral drugs, including anti-HIV drugs," the authors wrote.



<a href="http://www.youtube.com/watch?v=I1oLawChDvc" target="_blank" class="aeva_link bbc_link new_win" rel="nofollow">http://www.youtube.com/watch?v=I1oLawChDvc</a>


http://www.medicalnewstoday.com/articles/234664.php

LATEST COMMENTS

  1. SweetDaddy1 on: "Boko Haram No Longer Have Territorial Jurisdiction In Nigeria"– President Buhari
    "Boko Haram No Longer Have Territorial Jurisdiction In Nigeria" Change Of Name, they are ... 15 mins ago ago
  2. kennynaija on: What Is Wrong With This Photo (Brother & Sister Pose Edition)
    how  do u know they're brother and sister... 23 mins ago ago
  3. kaposky on: “I Am Not Regretting My Action"- Man Who Roasted His Neighbor For Wooing His Fiancee
    THIS MAN IS AN UNREPENTED SOUL. HE IS THE DEVIL HIMSELF... 36 mins ago ago
  4. slimber on: Pastor Arrested For Allegedly Killing Sex Worker In A Hotel For Rituals In Kogi State (Photos)
    People 're so wicked heartless and the so called pastor hmmm.mm Evil ... 1 hr ago ago
  5. slimber on: “I Am Not Regretting My Action"- Man Who Roasted His Neighbor For Wooing His Fiancee
    Just bcos of a woman you killed your fellow man nah waaa... 1 hr ago ago