((HIV/AID)) significant breakthrough in HIV/AIDS research

at 09:02 AM, 22/09/2011 (6 years ago)
(64 | Newbie) (m)
Body & Mind - HEALTH
U.S. Gamers Crack Puzzle in AIDS Research that Stumped Scientists for Years

Published September 19, 2011

| NewsCore

      Print
      Email
      Share

Foldit

University of Washington

Foldit is an experimental video game about protein folding that produces real-world results.

In just three weeks, online gamers deciphered the structure of a retrovirus protein that has stumped scientists for over a decade, and a study out Sunday says their breakthrough opens doors for a new AIDS drug design.

The protein, called a protease, plays a critical role in how some viruses, including HIV, multiply. Intensive research has been underway to find AIDS drugs that can deactivate proteases, but scientists were hampered by their inability to crack the enzyme's structure.

Looking for a solution, researchers at the University of Washington turned to Foldit, a program created by the university a few years ago that transforms problems of science into competitive computer games, and challenged players to use their three-dimensional problem-solving skills to build accurate models of the protein.

With days, the gamers generated models good enough for the researchers to refine into an accurate portrayal of the enzyme's structure. What's more, the scientists identified parts of the molecule that are likely targets for drugs to block the enzyme.

"These features provide opportunities for the design of antiretroviral drugs, including anti-HIV drugs," the authors wrote.



<a href="http://www.youtube.com/watch?v=I1oLawChDvc" target="_blank" class="aeva_link bbc_link new_win" rel="nofollow">http://www.youtube.com/watch?v=I1oLawChDvc</a>


http://www.medicalnewstoday.com/articles/234664.php

LATEST COMMENTS

  1. waffibabe on: Kemi Olunloyo Launch Another Disgusting Hate Attack On Linda Ikeji (Hot Details)
    This evil woman should be arrested.I was angry at a pastor that have her arrested some time ago.now ... 21 mins ago ago
  2. waffibabe on: Linda Ikeji Unveils Her Baby's Face On Her Birthday (Photos)
    Congratulations ma, jealous kemi can go and hang herself.Linda rock... 26 mins ago ago
  3. waffibabe on: Linda Ikeji Unveils Her Baby's Face On Her Birthday (Photos)
    Congratulations ma, jealous kemi can go and hang herself.Linda rock... 26 mins ago ago
  4. Upbendel on: "Kill Yourself" - Wizkid Replies Khloe Over Babymama Money Hungry Hoes
    Real African Vs African American?... 1 hr ago ago
  5. Upbendel on: CRAZY CAMEL! See The Beautiful Mini Jeep Made By A Nigerian Man, Andy Acka (Photos)
    Nice brand name, Love it!... 1 hr ago ago