Matthew Green had been critically ill, suffering from end-stage failure of both chambers of his heart.
But today he was preparing to return home after undergoing the ground-breaking surgery at Papworth Hospital, near Cambridge.
Doctors at the hospital have previously implanted a total artificial heart but this is the first time a patient has been well enough to leave hospital and go home.
The operation - which has also been completed successfully in the United States and parts of Europe - could help cut transplant waiting times in the future.
Mr Green said: "Two years ago I was cycling nine miles to work and nine miles back every day but by the time I was admitted to hospital I was struggling to walk even a few yards.
"I am really excited about going home and just being able to do the everyday things that I haven't been able to do for such a long time such as playing in the garden with my son and cooking a meal for my family.
"I want to thank all the wonderful staff at Papworth Hospital who have been looking after me and who have made it possible for me to return home to my family."
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