HIV CURE: Eureka! Toxin in bee venom kills HIV

Date: 17-03-2013 7:05 pm (11 years ago) | Author: Direct
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- at 17-03-2013 07:05 PM (11 years ago)
(m)
An important step toward developing a v*g*nal gel that may prevent the spread of human immuno deficiency virus, HIV, may have been achieved following the discovery that nanoparticles carrying a toxin found in bee venom can destroy HIV while leaving surrounding cells unharmed.



Researchers at Washington University School of Medicine in St. Louis who made discovery which is published the current issue of Antiviral Therapy, hope that in places where HIV is running rampant, people could use this gel as a preventive measure to stop the initial infection.

Bee venom contains a potent toxin called melittin that can poke holes in the protective envelope that surrounds HIV, and other viruses. Large amounts of free melittin can cause a lot of damage. Indeed, in addition to anti-viral therapy..

The new study shows that melittin loaded onto these nanoparticles does not harm normal cells. That’s because Hood added protective bumpers to the nanoparticle surface. When the nanoparticles come into contact with normal cells, which are much larger in size, the particles simply bounce off. HIV, on the other hand, is even smaller than the nanoparticle, so HIV fits between the bumpers and makes contact with the surface of the nanoparticle, where the bee toxin awaits.

Melittin on the nanoparticles fuses with the viral envelope. The melittin forms little pore-like attack complexes and ruptures the envelope, stripping it off the virus.

An advantage of this approach is that the nanoparticle attacks an essential part of the virus’ structure. In contrast, most anti-HIV drugs inhibit the virus’s ability to replicate. But this anti-replication strategy does nothing to stop initial infection, and some strains of the virus have found ways around these drugs and reproduce anyway.

The scientists, who say they are attacking an inherent physical property of HIV, note that, theoretically, there isn’t any way for the virus to adapt to that. The virus has to have a protective coat, a double-layered membrane that covers the virus.

Beyond prevention in the form of a v*g*nal gel, there is potential for using nanoparticles with melittin as therapy for existing HIV infections, especially those that are drug-resistant. The nanoparticles could be injected intravenously and, in theory, would be able to clear HIV from the blood stream.

The basic particle that we are using in these experiments was developed many years ago as an artificial blood product. Although it didn’t work very well for delivering oxygen, but it circulates safely in the body and gives nice platform that can be adapted to fight different kinds of infections.
Since melittin attacks double-layered membranes indiscriminately, this concept is not limited to HIV. Many viruses, including hepatitis B and C, rely on the same kind of protective envelope and would be vulnerable to melittin-loaded nanoparticles.

Posted: at 17-03-2013 07:05 PM (11 years ago) | Hero
- praytoGod4help at 17-03-2013 07:48 PM (11 years ago)
(m)
Another story
Posted: at 17-03-2013 07:48 PM (11 years ago) | Upcoming
Reply
- emexix at 17-03-2013 07:53 PM (11 years ago)
(m)
Ehen.... Means skin to skin without fear. Yeeeeeehhhh
Posted: at 17-03-2013 07:53 PM (11 years ago) | Newbie
Reply
- beatrice22 at 17-03-2013 08:02 PM (11 years ago)
(f)
Quote from: emexix on 17-03-2013 07:53 PM
Ehen.... Means skin to skin without fear. Yeeeeeehhhh
do u know what u are saying? may God help u.
Posted: at 17-03-2013 08:02 PM (11 years ago) | Upcoming
Reply
- zoe61 at 17-03-2013 08:19 PM (11 years ago)
(f)
 Grin Grin Grin Grin
Posted: at 17-03-2013 08:19 PM (11 years ago) | Hero
Reply
- etibaba at 17-03-2013 08:23 PM (11 years ago)
(m)
Quote from: emexix on 17-03-2013 07:53 PM
Ehen.... Means skin to skin without fear. Yeeeeeehhhh
I pity u

Posted: at 17-03-2013 08:23 PM (11 years ago) | Gistmaniac
Reply
- micc at 17-03-2013 08:32 PM (11 years ago)
(m)
Thank God am married so I don't need it at all at all
Posted: at 17-03-2013 08:32 PM (11 years ago) | Hero
Reply
- PidginMOUTH at 17-03-2013 08:35 PM (11 years ago)
(m)
oboy Micc u still need am o  Grin Grin Grin Grin
Posted: at 17-03-2013 08:35 PM (11 years ago) | Hero
Reply
- Starship at 17-03-2013 08:37 PM (11 years ago)
(m)
Useless discovery.... Prevention is better than cure.... Wetn be science to God's WORD???
Posted: at 17-03-2013 08:37 PM (11 years ago) | Upcoming
Reply
- Keffejude at 17-03-2013 08:40 PM (11 years ago)
(m)
Quote from: beatrice22 on 17-03-2013 08:02 PM
do u know what u are saying? may God help u.
Sharrrap there although its obvious d poster is simply playing a prank, na una when dey form dey 4k pass mtchew backyard ashawo...when last did u go 4 an HIV test?  Angry
Posted: at 17-03-2013 08:40 PM (11 years ago) | Gistmaniac
Reply
- 1daful at 17-03-2013 08:47 PM (11 years ago)
(f)
Another lies.

Posted: at 17-03-2013 08:47 PM (11 years ago) | Gistmaniac
Reply
- steve232 at 17-03-2013 08:49 PM (11 years ago)
(m)
Quote from: emexix on 17-03-2013 07:53 PM
Ehen.... Means skin to skin without fear. Yeeeeeehhhh
hmmm Roll Eyes Roll Eyes Roll Eyes Roll Eyes
Posted: at 17-03-2013 08:49 PM (11 years ago) | Gistmaniac
Reply
- paulohking at 17-03-2013 09:21 PM (11 years ago)
(m)
Hope it is a true discovery
Posted: at 17-03-2013 09:21 PM (11 years ago) | Hero
Reply
- dlimelite at 17-03-2013 09:35 PM (11 years ago)
(f)
hmmmm
Posted: at 17-03-2013 09:35 PM (11 years ago) | Hero
Reply
- oxSleekxo at 17-03-2013 09:48 PM (11 years ago)
(f)
[color=greenhmmm bees?? Goodluck!!][/color]

Posted: at 17-03-2013 09:48 PM (11 years ago) | Newbie
Reply
- beatrice22 at 17-03-2013 10:07 PM (11 years ago)
(f)
Quote from: Keffejude on 17-03-2013 08:40 PM
Sharrrap there although its obvious d poster is simply playing a prank, na una when dey form dey 4k pass mtchew backyard ashawo...when last did u go 4 an HIV test?  Angry
nobody say make u nor 4k as u like, ok ?  if u like 4k dog ,H:I:V nor dey show 4 face. mtchewwwwwwwwww. u dey go do H:I:V test everyday because u dey 4k anyhow like dog,... go and get a life , AIDS is real
Posted: at 17-03-2013 10:07 PM (11 years ago) | Upcoming
Reply
- NYPDmike at 17-03-2013 11:35 PM (11 years ago)
(m)
Stay out of crime people....................
Posted: at 17-03-2013 11:35 PM (11 years ago) | Upcoming
Reply
- osarobo62 at 17-03-2013 11:48 PM (11 years ago)
(m)
Quote from: emexix on 17-03-2013 07:53 PM
Ehen.... Means skin to skin without fear. Yeeeeeehhhh
Grin Grin Grin Grin in your dream
Posted: at 17-03-2013 11:48 PM (11 years ago) | Hero
Reply
- osarobo62 at 17-03-2013 11:50 PM (11 years ago)
(m)
Quote from: micc on 17-03-2013 08:32 PM
Thank God am married so I don't need it at all at all
Nice to have a trusted partner and be trusted.
Posted: at 17-03-2013 11:50 PM (11 years ago) | Hero
Reply
- nzewyte at 18-03-2013 12:00 AM (11 years ago)
(m)
Ur comments r all laughable...... Permit 2 laff.........

Posted: at 18-03-2013 12:00 AM (11 years ago) | Gistmaniac
Reply
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